DKK-Toa Yamagata Co.
Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Iwate University
Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Iwate University
Institute of Livestock and Grassland Science, NARO
Awaji Agricultural Technology Center
Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Iwate University , Department of Animal Resources Science, Dankook University
Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Iwate University
登録日
2022-09-20
雑誌名
Journal of Veterinary Science
巻
22
号
3
ページ
e34
発行年
2021-04-19
ISSN
1229845X
抄録
Anti-lipopolysaccharide (LPS) antibody administration has the potential benefits of neutralizing and consequently controlling rumen-derived LPS during subacute ruminal acidosis. Four Holstein bulls were used in this crossover study with a 2-week wash-out period. Anti-LPS antibody (0 or 4 g) was administered once daily for 14 days. Significantly lower ruminal LPS and higher 1-h mean ruminal pH were identified in the 4 g group. However, blood metabolites, acute-phase proteins, cytokines, and hepatic transcriptomes were not different between the two groups. Therefore, anti-LPS antibody administration mitigated ruminal LPS release and pH depression without accompanying responses in acute-phase inflammation or hepatic transcriptomic expression.
Anti-lipopolysaccharide antibody mitigates ruminal lipopolysaccharide release without acute-phase inflammation or liver transcriptomic responses in Holstein bulls
jvs-v22pe34
(1.62MB)
