| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2012-01-23 |
| タイトル |
|
|
タイトル |
Enhancement of Chemotactic Response to Sodium Acetate in the Nematode Caenorhabditis elegans |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Chemotaxis |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
dopamine |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
nematode |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
sensitization |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
sodium acetate |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Matsuura, Tetsuya
Oda, Takayuki
Hayashi, Genta
Sugisaki, Daisuke
Ichinohe, Mitsuyuki
|
| 著者(機関) |
|
|
値 |
Department of Welfare Engineering, Faculty of Engineering, Iwate University |
| 登録日 |
|
|
日付 |
2012-01-23 |
| 書誌情報 |
Zoological Science
巻 27,
号 8,
p. 629-637,
発行日 2010-08-01
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0289-0003 |
| Abstract |
|
|
内容記述タイプ |
Other |
|
内容記述 |
In this study, we investigated the chemotactic response of a wild-type (N2) nematode (Caenorhabditis elegans) to a water-soluble attractant, sodium acetate, after pre-exposure to the chemical. The chemotactic response to 1.0 M sodium acetate of the non-exposed control nematodes was lower than that of the nematodes that were pre-exposed to 1.0 M sodium acetate for 90 min (p < 0.05). The increase in the response to sodium acetate was observed up to 6 hr, but not at 12 hr after exposure. To clarify the mechanism of this enhancement of the chemotactic response, several mutants were used. The chemotactic response of pre-exposed tph-1 and bas-1 mutants, whose main defect was serotonin secretion, was enhanced in comparison with that of the control mutants (p < 0.01). However, cat-1 and cat-2 mutants, which are respectively defective in serotonin and dopamine secretion and dopamine secretion only, showed no enhancement of the chemotactic response to sodium acetate, even when pre-exposed to this chemical. When the cat-1 and cat-2 mutants were pre-exposed to sodium acetate and bred in the presence of 40 mM dopamine, these mutants showed enhanced chemotactic response to sodium acetate (p < 0.05). These results suggest that the enhancement of chemotactic response to sodium acetate after pre-exposure to this chemical is modulated by dopaminergic neurotransmission. |
| 出版者 |
|
|
出版者 |
Zoological Society of Japan |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.2108/zsj.27.629 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
zs-v27n8p629-637.pdf (255.0 kB)
