{"created":"2023-05-15T12:08:47.595679+00:00","id":14122,"links":{},"metadata":{"_buckets":{"deposit":"47de82e2-14e2-4a3e-b9d3-39b611e0ff86"},"_deposit":{"created_by":3,"id":"14122","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"14122"},"status":"published"},"_oai":{"id":"oai:iwate-u.repo.nii.ac.jp:00014122","sets":["1523:1528:1551:1804"]},"author_link":["87002","87001"],"item_41_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-03-31","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"129","bibliographicPageStart":"125","bibliographicVolumeNumber":"15","bibliographic_titles":[{"bibliographic_title":"岩手大学教育学部附属教育実践総合センター研究紀要"},{"bibliographic_title":"The journal of Clinical Research Center for Child Development and Educational Practices","bibliographic_titleLang":"en"}]}]},"item_41_date_6":{"attribute_name":"登録日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2017-02-14"}]},"item_41_description_12":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"ネグレリアフォーレリ(Naegleria fowleri)は温水を好む病原性アメーバで，ヒトの鼻腔から大脳に侵入し大脳組織の軟化や出血を伴う壊死（原発性アメーバ性髄膜脳炎; PAM）を引き起こす。PAMの進行は急速で有効な治療法もなく，約2週間でほとんどの患者が死に至り，臨床では僅かな生存例があるのみである。筆者は，ネグレリアフォーレリの分子生物学的解析を行い本病原体の特性と病原性を理解するとともに迅速簡便な検出法の開発を目的として，本邦で分離された株について次世代シーケンサによる全ゲノム解析を行った。その結果，本株のゲノムサイズは27.61Mb，GC含量は35.7%，遺伝子数は15108であることが分かった。また，青色光受容ドメインを有するタンパク質が2種類コードされていることが分かり，本病原体が青色光に応答する可能性が示唆された。","subitem_description_type":"Other"}]},"item_41_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"YASUKAWA, Hiro"}]}]},"item_41_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15113/00014116","subitem_identifier_reg_type":"JaLC"}]},"item_41_publisher_14":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"岩手大学教育学部附属教育実践総合センター"}]},"item_41_source_id_25":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA11844473","subitem_source_identifier_type":"NCID"}]},"item_41_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13472216","subitem_source_identifier_type":"ISSN"}]},"item_41_text_4":{"attribute_name":"著者(機関)","attribute_value_mlt":[{"subitem_text_value":"岩手大学教育学部"}]},"item_41_version_type_27":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"安川, 洋生"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-14"}],"displaytype":"detail","filename":"jcrc-n15p125-129.pdf","filesize":[{"value":"1.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"jcrc-n15p125-129.pdf ","url":"https://iwate-u.repo.nii.ac.jp/record/14122/files/jcrc-n15p125-129.pdf"},"version_id":"a6475df9-dae3-4697-a691-870f706af679"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"致死性病原体ネグレリアフォーレリの全ゲノム解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"致死性病原体ネグレリアフォーレリの全ゲノム解析"},{"subitem_title":"Whole Genome Analysis of the Pathogenic Amoeba Naegleria fowleri Isolated from a Japanese Patient","subitem_title_language":"en"}]},"item_type_id":"41","owner":"3","path":["1804"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-02-14"},"publish_date":"2017-02-14","publish_status":"0","recid":"14122","relation_version_is_last":true,"title":["致死性病原体ネグレリアフォーレリの全ゲノム解析"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-05-15T14:06:59.460316+00:00"}