{"created":"2023-05-15T12:09:52.669118+00:00","id":15465,"links":{},"metadata":{"_buckets":{"deposit":"03a42f91-50b5-4612-83a2-59affbb69768"},"_deposit":{"created_by":19,"id":"15465","owners":[19],"pid":{"revision_id":0,"type":"depid","value":"15465"},"status":"published"},"_oai":{"id":"oai:iwate-u.repo.nii.ac.jp:00015465","sets":["1504:1510"]},"author_link":["93371","93375","93377","93373","93374","93376","93372"],"item_16_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-08-18","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"13974","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"Scientific Reports"}]}]},"item_16_description_11":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Two elements of neural information processing have primarily been proposed: firing rate and spike timing of neurons. In the case of synaptic plasticity, although spike-timing-dependent plasticity (STDP) depending on presynaptic and postsynaptic spike times had been considered the most common rule, recent studies have shown the inhibitory nature of the brain in vivo for precise spike timing, which is key to the STDP. Thus, the importance of the firing frequency in synaptic plasticity in vivo has been recognized again. However, little is understood about how the frequency-dependent synaptic plasticity (FDP) is regulated in vivo. Here, we focused on the presynaptic input pattern, the intracellular calcium decay time constants, and the background synaptic activity, which vary depending on neuron types and the anatomical and physiological environment in the brain. By analyzing a calcium-based model, we found that the synaptic weight differs depending on these factors characteristic in vivo, even if neurons receive the same input rate. This finding suggests the involvement of multifaceted factors other than input frequency in FDP and even neural coding in vivo.","subitem_description_type":"Abstract"}]},"item_16_publisher_14":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer Nature"}]},"item_16_relation_17":{"attribute_name":"関係URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Multicoding in neural information transfer suggested by mathematical analysis of the frequency‑dependent synaptic plasticity in vivo"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.nature.com/articles/s41598-020-70876-4#Sec1","subitem_relation_type_select":"URI"}}]},"item_16_relation_26":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1038/s41598-020-70876-4","subitem_relation_type_select":"DOI"}}]},"item_16_rights_18":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© The Author(s) 2020"}]},"item_16_rights_19":{"attribute_name":"権利URI","attribute_value_mlt":[{"subitem_rights":"http://creativecommons.org/licenses/by/4.0/"}]},"item_16_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"20452322","subitem_source_identifier_type":"ISSN"}]},"item_16_text_4":{"attribute_name":"著者(機関)","attribute_value_mlt":[{"subitem_text_value":"Department of Sports and Medical Science, Kokushikan University, Department of Neuroscience, Research Center for Mathematical Medicine, Department of Physics, Faculty of Science Division I, Tokyo University of Science"},{"subitem_text_value":"Department of Applied Physics, Faculty of Science Division I, Tokyo University of Science"},{"subitem_text_value":"Department of Neuroscience, Research Center for Mathematical Medicine"},{"subitem_text_value":"Department of Sports and Medical Science, Kokushikan University"},{"subitem_text_value":"Laboratory of Veterinary Biochemistry and Cell Biology, Faculty of Agriculture, Iwate University"},{"subitem_text_value":"Department of Sports and Medical Science, Kokushikan University"},{"subitem_text_value":"Department of Physics, Faculty of Science Division I, Tokyo University of Science"}]},"item_16_version_type_27":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"HATA, Katsuhiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"ARAKI, Osamu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YOKOI, Osamu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KUSAKABE, Tatsumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YAMAMOTO, Yoshio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"ITO, Susumu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"NIKUNI, Tetsuro"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-12-07"}],"displaytype":"detail","filename":"sr-v10p13974.pdf","filesize":[{"value":"2.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"sr-v10p13974","url":"https://iwate-u.repo.nii.ac.jp/record/15465/files/sr-v10p13974.pdf"},"version_id":"bb484dbe-cfa5-4091-a12f-f26469dadf28"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Multicoding in neural information transfer suggested by mathematical analysis of the frequency‑dependent synaptic plasticity in vivo","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Multicoding in neural information transfer suggested by mathematical analysis of the frequency‑dependent synaptic plasticity in vivo"}]},"item_type_id":"16","owner":"19","path":["1510"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-12-07"},"publish_date":"2021-12-07","publish_status":"0","recid":"15465","relation_version_is_last":true,"title":["Multicoding in neural information transfer suggested by mathematical analysis of the frequency‑dependent synaptic plasticity in vivo"],"weko_creator_id":"19","weko_shared_id":-1},"updated":"2023-05-15T13:04:13.022959+00:00"}