@article{oai:iwate-u.repo.nii.ac.jp:00015507,
 author = {KATAYAMA, Masafumi and ONUMA, Manabu and FUKUDA, Tomokazu},
 issue = {4},
 journal = {The journal of poultry science},
 month = {},
 note = {Cultured cells are a useful resource for poultry scientists, since these cells allow scientists to evaluate biological responses to conditions such as infectious diseases in vitro while mimicking the whole-body response in birds. However avian cell culture requires an optimized basal medium, and there are currently relatively few options for this basal medium (medium 199 and KAv-1). This means that there is still room for the development of an optimal basal medium for avian cell culture. Here we compare KAv-1 medium, Dulbecco's modified Eagle medium (DMEM) and medium 199 during the culture of chick fibroblasts and determine that KAv-1 remains the optimal medium for these assays. Our results show that DNA damage is reduced in fibroblasts cultured in the KAv-1 medium, when compared to both DMEM and Medium 199 and that these cells also display improved growth dynamics in KAv-1 medium when compared to both DMEM and medium 199. To the best of our knowledge, this is the first study to describe a comparative analysis of culture media for avian cells, which would provide useful information for poultry scientists.},
 pages = {270--279},
 title = {KAv-1 is Better Suited to Chick Fibroblast Culture than DMEM or 199 Media},
 volume = {58},
 year = {2021}
}