{"created":"2023-05-15T12:10:07.857883+00:00","id":15776,"links":{},"metadata":{"_buckets":{"deposit":"3f478880-8f78-441e-bc0c-8e4c04d4351b"},"_deposit":{"created_by":19,"id":"15776","owners":[19],"pid":{"revision_id":0,"type":"depid","value":"15776"},"status":"published"},"_oai":{"id":"oai:iwate-u.repo.nii.ac.jp:00015776","sets":["1515:1519"]},"author_link":["95053","95052","95050","95049","95048","95051","95054"],"item_16_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-09-13","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"104679","bibliographicVolumeNumber":"86","bibliographic_titles":[{"bibliographic_title":"Journal of Functional Foods"}]}]},"item_16_date_6":{"attribute_name":"登録日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2022-08-29"}]},"item_16_description_11":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Antioxidant peptide, referred as Trp-Gly-Pro-Gly-Val-Glu (WGPGVE), was isolated and identified from porcine plasma which was hydrolysised 5 h by alkaline protease. The sequence of WGPGVE had hydrophobic amino acids G, V, aromatic amino acids W, and acidic amino acid E, as well as its values of hydroxyl, ABTS, DPPH radicals scavenging rates and iron chelating rate were improved by 30.15%, 10.05%, 38.69%, 51.40% respectively, compared to glutathione (29.32%, 81.06%, 25.43%, 17.82%). Moreover, under in vitro digestion model, it exhibited stable antioxidation (50.15%, 92.49%, 24.29%, 35.35%) after the hydrolysis effect of pepsin and trypsin. Additionally, WGPGVE could protect HepG2 cells against H2O2 by promoting the expression of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) and decreasing reactive oxygen species (ROS), malondialdehyde (MDA) contents. Thus, the new sequence antioxidant peptide could be potentially used in pharmaceuticals or functional foods and promote the application of porcine plasma in food.","subitem_description_type":"Abstract"}]},"item_16_link_13":{"attribute_name":"抄録（URL）","attribute_value_mlt":[{"subitem_link_text":"Identification of a new antioxidant peptide from porcine plasma by in vitro digestion and its cytoprotective effect on H2O2 induced HepG2 model","subitem_link_url":"https://www.sciencedirect.com/science/article/pii/S1756464621003285"}]},"item_16_publisher_14":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier Ltd."}]},"item_16_relation_26":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1016/j.jff.2021.104679","subitem_relation_type_select":"DOI"}}]},"item_16_rights_18":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2021 The Authors."}]},"item_16_rights_19":{"attribute_name":"権利URI","attribute_value_mlt":[{"subitem_rights":"http://creativecommons.org/licenses/by-nc-nd/4.0/"}]},"item_16_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"17564646","subitem_source_identifier_type":"ISSN"}]},"item_16_text_4":{"attribute_name":"著者(機関)","attribute_value_mlt":[{"subitem_text_value":"Institute of Food Engineering, College of Biosystems Engineering and Food Science, Zhejiang University ,  College of Food Science and Technology, Hainan Tropical Ocean University"},{"subitem_text_value":"Key Laboratory of Animal Protein Food Processing Technology of Zhejiang Province, Ningbo University"},{"subitem_text_value":"Institute of Food Engineering, College of Biosystems Engineering and Food Science, Zhejiang University ,  College of Food Science and Technology, Hainan Tropical Ocean University"},{"subitem_text_value":"Faculty of Science and Engineering, Iwate University"},{"subitem_text_value":"Faculty of Science and Engineering, Iwate University"},{"subitem_text_value":"Institute of Food Engineering, College of Biosystems Engineering and Food Science, Zhejiang University ,  Key Laboratory of Health Risk Factors for Seafood of Zhejiang Province, College of Food Science and harmacy,Zhejiang Ocean University"},{"subitem_text_value":"College of Food Science and Technology, Hainan Tropical Ocean University"}]},"item_16_version_type_27":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"LI, Gaoshang"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"ZHAN, Junqi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"HU, Lingping"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YUAN, Chunhong"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TAKAKI, Koichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YING, Xiaoguo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"HU, Yaqin"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-08-29"}],"displaytype":"detail","filename":"jff-v86p104679.pdf","filesize":[{"value":"7.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"jff-v86p104679","url":"https://iwate-u.repo.nii.ac.jp/record/15776/files/jff-v86p104679.pdf"},"version_id":"f1d88b10-7f49-4fc2-b93c-03171cb04cca"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Antioxidant","subitem_subject_scheme":"Other"},{"subitem_subject":"HepG2 cells","subitem_subject_scheme":"Other"},{"subitem_subject":"In vitro digestion","subitem_subject_scheme":"Other"},{"subitem_subject":"Peptide","subitem_subject_scheme":"Other"},{"subitem_subject":"Porcine plasma","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Identification of a new antioxidant peptide from porcine plasma by in vitro digestion and its cytoprotective effect on H2O2 induced HepG2 model","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Identification of a new antioxidant peptide from porcine plasma by in vitro digestion and its cytoprotective effect on H2O2 induced HepG2 model"}]},"item_type_id":"16","owner":"19","path":["1519"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-08-29"},"publish_date":"2022-08-29","publish_status":"0","recid":"15776","relation_version_is_last":true,"title":["Identification of a new antioxidant peptide from porcine plasma by in vitro digestion and its cytoprotective effect on H2O2 induced HepG2 model"],"weko_creator_id":"19","weko_shared_id":-1},"updated":"2023-05-15T12:51:35.505979+00:00"}