{"created":"2023-05-15T12:10:08.646925+00:00","id":15793,"links":{},"metadata":{"_buckets":{"deposit":"5a069cfe-3237-44b0-8602-70a580673c42"},"_deposit":{"created_by":19,"id":"15793","owners":[19],"pid":{"revision_id":0,"type":"depid","value":"15793"},"status":"published"},"_oai":{"id":"oai:iwate-u.repo.nii.ac.jp:00015793","sets":["1504:1510"]},"author_link":["95172","95168","95171","95169","95163","95162","95165","95166","95167","95161","95173","95164","95170"],"item_16_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageStart":"eabd9135","bibliographicVolumeNumber":"7","bibliographic_titles":[{"bibliographic_title":"Science Advances"}]}]},"item_16_date_6":{"attribute_name":"登録日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2022-09-15"}]},"item_16_description_11":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Domestic cats and other felids rub their faces and heads against catnip (Nepeta cataria) and silver vine (Actinidia polygama) and roll on the ground as a characteristic response. While this response is well known, its biological function and underlying mechanism remain undetermined. Here, we uncover the neurophysiological mechanism and functional outcome of this feline response. We found that the iridoid nepetalactol is the major component of silver vine that elicits this potent response in cats and other felids. Nepetalactol increased plasma β-endorphin levels in cats, while pharmacological inhibition of μ-opioid receptors suppressed the classic rubbing response. Rubbing behavior transfers nepetalactol onto the faces and heads of respondents where it repels the mosquito, Aedes albopictus. Thus, self-anointing behavior helps to protect cats against mosquito bites. The characteristic response of cats to nepetalactol via the μ-opioid system provides an important example of chemical pest defense using plant metabolites in nonhuman mammals.","subitem_description_type":"Abstract"}]},"item_16_link_13":{"attribute_name":"抄録（URL）","attribute_value_mlt":[{"subitem_link_text":"The characteristic response of domestic cats to plant iridoids allows them to gain chemical defense against mosquitoes","subitem_link_url":"https://www.science.org/doi/10.1126/sciadv.abd9135"}]},"item_16_publisher_14":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"American Association for the Advancement of Science"}]},"item_16_relation_26":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1126/sciadv.abd9135","subitem_relation_type_select":"DOI"}}]},"item_16_rights_18":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":" © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science."}]},"item_16_rights_19":{"attribute_name":"権利URI","attribute_value_mlt":[{"subitem_rights":"https://creativecommons.org/licenses/by-nc/4.0/"}]},"item_16_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"23752548","subitem_source_identifier_type":"ISSN"}]},"item_16_text_4":{"attribute_name":"著者(機関)","attribute_value_mlt":[{"subitem_text_value":"Department of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University"},{"subitem_text_value":"Department of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University"},{"subitem_text_value":"Mammalian Behaviour and Evolution Group, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus"},{"subitem_text_value":"Centre for Proteome Research, Institute of Systems, Molecular and Integrative Biology, University of Liverpool"},{"subitem_text_value":"Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University"},{"subitem_text_value":"Department of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University"},{"subitem_text_value":"Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University"},{"subitem_text_value":"Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University"},{"subitem_text_value":"Department of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University"},{"subitem_text_value":"Department of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University"},{"subitem_text_value":"Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University"},{"subitem_text_value":"Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University"},{"subitem_text_value":"Department of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University"}]},"item_16_version_type_27":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"UENOYAMA, Reiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MIYAZAKI, Tamako"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"HURST, Jane L."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"BEYNON, Robert J."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"ADACHI, Masaatsu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MUROOKA, Takanobu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"ONODA, Ibuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MIYAZAWA, Yu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KATAYAMA, Rieko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YAMASHITA, Tetsuro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KANEKO, Shuji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"NISHIKAWA, Toshio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MIYAZAKI, Masao"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-09-15"}],"displaytype":"detail","filename":"sa-v7n420peabd9135.pdf","filesize":[{"value":"4.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"sa-v7n420peabd9135","url":"https://iwate-u.repo.nii.ac.jp/record/15793/files/sa-v7n420peabd9135.pdf"},"version_id":"ef9f6213-53e8-429b-a037-68c5588d3ed5"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The characteristic response of domestic cats to plant iridoids allows them to gain chemical defense against mosquitoes","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The characteristic response of domestic cats to plant iridoids allows them to gain chemical defense against mosquitoes"}]},"item_type_id":"16","owner":"19","path":["1510"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-09-15"},"publish_date":"2022-09-15","publish_status":"0","recid":"15793","relation_version_is_last":true,"title":["The characteristic response of domestic cats to plant iridoids allows them to gain chemical defense against mosquitoes"],"weko_creator_id":"19","weko_shared_id":-1},"updated":"2023-05-15T12:50:55.020274+00:00"}