@article{oai:iwate-u.repo.nii.ac.jp:00015795,
 author = {MIZUGUCHI, Hitoshi and KIZAI, Keiichiro and KIMURA, Atsushi and KUSHIBIKI, Shiro and IKUTA, Kentaro and KIM, Yo-Han and SATO, Shigeru},
 issue = {3},
 journal = {Journal of Veterinary Science},
 month = {Apr},
 note = {Anti-lipopolysaccharide (LPS) antibody administration has the potential benefits of neutralizing and consequently controlling rumen-derived LPS during subacute ruminal acidosis. Four Holstein bulls were used in this crossover study with a 2-week wash-out period. Anti-LPS antibody (0 or 4 g) was administered once daily for 14 days. Significantly lower ruminal LPS and higher 1-h mean ruminal pH were identified in the 4 g group. However, blood metabolites, acute-phase proteins, cytokines, and hepatic transcriptomes were not different between the two groups. Therefore, anti-LPS antibody administration mitigated ruminal LPS release and pH depression without accompanying responses in acute-phase inflammation or hepatic transcriptomic expression.},
 title = {Anti-lipopolysaccharide antibody mitigates ruminal lipopolysaccharide release without acute-phase inflammation or liver transcriptomic responses in Holstein bulls},
 volume = {22},
 year = {2021}
}