| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-12-11 |
| タイトル |
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|
タイトル |
Life table analysis of feline polycystic kidney disease in Japan |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
cumulative survival rate |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
feline polycystic kidney disease |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
follow-up investigation |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
life expectancy |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
life table analysis |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
ENOMOTO, Takeru
KOBAYASHI, Saori
ISHIGURO, Naomi
|
| 登録日 |
|
|
日付 |
2025-12-11 |
|
日付タイプ |
Created |
| 書誌情報 |
en : The Journal of Veterinary Medical Science
巻 87,
号 7,
p. 791-797,
ページ数 7,
発行日 2025-05-20
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| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
1347-7439 |
| ISSN |
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収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0916-7250 |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Feline polycystic kidney disease (PKD) is an inherited renal disorder observed in various breeds. Analyses of life expectancy and distribution of age at death among cats are not well documented. The current study preliminarily assessed life expectancy, cumulative survival rates, and distribution of age at death in cats with PKD by performing a follow-up investigation. This retrospective cohort study was conducted on 300 cats that tested positive for the feline PKD1 variant (c.10063C >A) in Japan. A life table analysis was performed, and a distribution graph of age at death was generated. The life expectancy at birth was approximately 12.7 years, with a 5- and 10-year cumulative survival rates of 95.1% and 61.3%, respectively. Of the 300 cats, 48 (16.0%) progressed to uremia, and 62 (20.7%) died of renal failure and other causes. The median age at death in 62 cats was 8 years, with the first decile being 5 years. The highest number of deaths was at the age of 7 years. The cumulative survival rate began to decline significantly at the age of 6–7 years. This study first performed a survival analysis of feline PKD and provided an important basis for understanding the patterns of overall mortality associated with this genetic disorder. Our findings emphasized the importance of frequent examination at a young age, with consideration of the remarkable decrease in the cumulative survival rate between the ages of 6 and 7 years. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
The Japanese Society of Veterinary Science |
|
言語 |
en |
| 権利 |
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|
権利情報Resource |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
|
権利情報 |
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International |
|
言語 |
en |
| DOI |
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|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.1292/jvms.25-0080 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 助成情報 |
|
|
|
助成機関名 |
Japan Society for the Promotion of Science |
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|
言語 |
en |
|
|
研究課題番号タイプ |
JGN |
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|
研究課題番号 |
22K06000 |
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|
研究課題番号URI |
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K06000/ |
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|
研究課題名 |
猫遺伝性多発性嚢胞腎の個体別重症度・進行度の差異のメカニズム解明 |
|
|
言語 |
ja |
| 内容注記 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
This work was supported by JSPS KAKENHI (grant number:JP22K06000-0003). |
|
言語 |
en |
jvms-v87i7p791-797.pdf (1.1 MB)
