| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2008-12-09 |
| タイトル |
|
|
タイトル |
Suppression of Myofibrillar Protein Degradation after Refeeding in Young and Adult Mice |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
protein turnover |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
myofibrillar protein |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
dietary protein |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
3-methylhistidine |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
NAGASAWA, Takashi
KIKUCHI, Nobuhiro
ITO, Yoshiaki
YOSHIZAWA, Fumiaki
NISHIZAWA, Naoyuki
|
| 著者(機関) |
|
|
値 |
Food and Health Science, Faculty of Agriculture, Iwate University |
| 著者(機関) |
|
|
値 |
Food and Health Science, Faculty of Agriculture, Iwate University |
| 著者(機関) |
|
|
値 |
Food and Health Science, Faculty of Agriculture, Iwate University |
| 著者(機関) |
|
|
値 |
4Department of Animal Science, Faculty of Agriculture, Utsunomiya University |
| 著者(機関) |
|
|
値 |
Food and Health Science, Faculty of Agriculture, Iwate University |
| 登録日 |
|
|
日付 |
2008-12-09 |
| 書誌情報 |
Journal of nutritional science and vitaminology
巻 50,
号 3,
p. 227-230,
発行日 2004-01-01
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
03014800 |
| Abstract |
|
|
内容記述タイプ |
Other |
|
内容記述 |
A diet containing adequate amounts of protein rapidly suppresses myofibrillar protein degradation after refeeding in young rats and mice. However, it is unclear whether this suppression is seen in adult animals. This study was undertaken to compare dietary protein-induced suppression of myofibrillar protein degradation in young and adult mice. Reductions in rates of myofibrillar protein degradation measured by N^T-methylhistidine (MeHis) released from the isolated extensor digitorum longus muscle were found at 4 to 7 h after refeeding in both young (7-wk-old) and adult (8-mo-old) mice, indicating that the response time of feeding-induced suppression of myofibrillar protein degradation was the same. When young (8-wk-old) mice were fed a 20% casein diet (20C) for 1 h after 18 h starvation, the rate of myofibrillar protein degradation was significantly decreased at 4 h after refeeding ; however, mice fed a 10% casein diet (10C), 5% casein diet (5C), or protein-free diet (0C) did not show suppression of myofibrillar protein degradation. Adult (8-mo-old) mice fed 20C or 10C showed a reduction in the rate of MeHis release. The plasma concentration of leucine in young mice was only higher when they were fed 20C. Adult mice fed 20C or 10C showed higher plasma concentrations of leucine. These results suggest that postprandial suppression of myofibrillar protein degradation occurs in adult mice as in young mice, but the adult mice respond to a lower amount of dietary casein compared to the young mice. |
| 出版者 |
|
|
出版者 |
日本ビタミン学会 |
| 権利 |
|
|
権利情報 |
日本ビタミン学会 |
| 権利 |
|
|
権利情報 |
本文データは学協会の許諾に基づきCiNiiから複製したものである |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 異版である |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
http://ci.nii.ac.jp/naid/110002703991/ |
jnsv-v50n3p227-230.pdf (400.8 kB)
