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  1. 040 農学 Agriculture
  2. 学術雑誌掲載論文

Characterization of Novel Staphylococcal Enterotoxin-Like Toxin Type P

https://iwate-u.repo.nii.ac.jp/records/9092
https://iwate-u.repo.nii.ac.jp/records/9092
f7cfdd53-4274-4213-a3bf-c10a0a927c62
名前 / ファイル ライセンス アクション
ii-v73n9p5540-5546.pdf ii-v73n9p5540-5546.pdf (199.9 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2009-08-18
タイトル
タイトル Characterization of Novel Staphylococcal Enterotoxin-Like Toxin Type P
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Omoe, Katsuhiko

× Omoe, Katsuhiko

Omoe, Katsuhiko

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Imanishi, Ken’ichi

× Imanishi, Ken’ichi

Imanishi, Ken’ichi

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Hu, Dong-Liang

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Hu, Dong-Liang

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Kato, Hidehito

× Kato, Hidehito

Kato, Hidehito

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Fugane, Yoshitaku

× Fugane, Yoshitaku

Fugane, Yoshitaku

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Abe, Yohei

× Abe, Yohei

Abe, Yohei

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Hamaoka, Shoji

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Hamaoka, Shoji

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Watanabe, Yutaka

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Watanabe, Yutaka

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Nakane, Akio

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Nakane, Akio

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Uchiyama, Takehiko

× Uchiyama, Takehiko

Uchiyama, Takehiko

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Shinagawa, Kunihiro

× Shinagawa, Kunihiro

Shinagawa, Kunihiro

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著者(機関)
値 Department of Veterinary Medicine, Faculty of Agriculture, Iwate University
著者(機関)
値 Department of Microbiology and Immunology, Tokyo Women’s Medical University School of Medicine
著者(機関)
値 Department of Bacteriology, Hirosaki University School of Medicine
著者(機関)
値 Department of Microbiology and Immunology, Tokyo Women’s Medical University School of Medicine
著者(機関)
値 Department of Veterinary Medicine, Faculty of Agriculture, Iwate University
著者(機関)
値 Department of Veterinary Medicine, Faculty of Agriculture, Iwate University
著者(機関)
値 Department of Veterinary Medicine, Faculty of Agriculture, Iwate University
著者(機関)
値 Department of Veterinary Medicine, Faculty of Agriculture, Iwate University
著者(機関)
値 Department of Bacteriology, Hirosaki University School of Medicine
著者(機関)
値 Department of Microbiology and Immunology, Tokyo Women’s Medical University School of Medicine
著者(機関)
値 Department of Veterinary Medicine, Faculty of Agriculture, Iwate University
登録日
日付 2009-08-18
書誌情報 巻 73, 号 9, p. 5540-5546, 発行日 2005-01-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 0019-9567
Abstract
内容記述タイプ Other
内容記述 We investigated the biological properties of a novel staphylococcal enterotoxin (SE)-like toxin type P (SElP).
SElP induced a substantial proliferative response and the production of cytokines interleukin-2, gamma
interferon, tumor necrosis factor alpha, and interleukin-4 from human T cells when administered at a
concentration of 0.4 pM (0.01 ng/ml) or more. The expression of major histocompatibility complex class II
molecules on accessory cells was required for T-cell stimulation by SElP. SElP selectively stimulated a vast
number of human T cells bearing receptors V 5.1, 6, 8, 16, 18, and 21.3. These results indicated that SElP acts
as a superantigen. SElP proved to be emetic in the house musk shrew emetic assay, although at a relatively high
dose (50 to 150 g/animal). A quantitative assay of SElP production with 30 Staphylococcus aureus strains
harboring selp showed that 60% of these strains produced significant amounts of SElP in vitro. All 10 strains
carrying seb and selp produced SEB but not SElP, suggesting the inactivation of the selp locus in S. aureus
strains with a particular se gene constitution.
出版者
出版者 INFECTION AND IMMUNITY
権利
権利情報 Copyright © 2005, American Society for Microbiology
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 10.1128/IAI.73.9.5540–5546.2005
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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