{"created":"2023-05-15T12:04:32.262361+00:00","id":9095,"links":{},"metadata":{"_buckets":{"deposit":"e23f3731-f2af-4445-ad75-20bd42d236cf"},"_deposit":{"created_by":3,"id":"9095","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"9095"},"status":"published"},"_oai":{"id":"oai:iwate-u.repo.nii.ac.jp:00009095","sets":["1504:1510"]},"author_link":["71698","71699","71700"],"item_16_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-01-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"133","bibliographicPageStart":"129","bibliographicVolumeNumber":"454","bibliographic_titles":[{"bibliographic_title":"Neuroscience Letters"}]}]},"item_16_date_6":{"attribute_name":"登録日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2009-09-14"}]},"item_16_description_12":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"TREK belongs to a subfamily of tandem pore domain K+ channels, and consists of three subunits, TREK-1, TREK-2 and TRAAK. We examined the distribution of TREK-1, TREK-2 and TRAAK immunoreactive neurons in rat trigeminal sensory neurons. In the trigeminal ganglia, 31%, 43% and 60% of neurons were immunoreactive for TREK-1, TREK-2 and TRAAK, respectively. Mean sizes of TREK-1, TREK-2 and TRAAK immunoreactive trigeminal ganglion neurons were 447 ± 185, 445 ± 23 and 492 ± 12 mm2, respectively. Furthermore, TREK channels were colocalized with cationic TRP channels, TRPV1, TRPV2 and TRPM8. TREK-1 immunoreactive neurons were colocalized with TRPV1 (57%), TRPV2 (11%) and TRPM8 (33%). TREK-2-immunoreactive neurons were colocalized with TRPV1 (33%), TRPV2 (9%) and TRPM8 (19%). TRAAK immunoreactive neurons were colocalized with TRPV1 (47%), TRPV2 (10%) and TRPM8 (22%). The present results revealed that TREK-1, TREK-2 and TRAAK channels colocalized with thermosensitive TRP channels in some small trigeminal ganglion neurons.","subitem_description_type":"Other"}]},"item_16_publisher_14":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_16_relation_26":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.neulet.2009.02.069","subitem_relation_type_select":"DOI"}}]},"item_16_rights_18":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2009 Elsevier Ireland"}]},"item_16_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0304-3940","subitem_source_identifier_type":"ISSN"}]},"item_16_text_4":{"attribute_name":"著者(機関)","attribute_value_mlt":[{"subitem_text_value":"Laboratory of Veterinary Biochemistry and Cell Biology, Faculty of Agriculture, Iwate University"},{"subitem_text_value":"Laboratory of Veterinary Anatomy, Faculty of Agriculture, Iwate University"},{"subitem_text_value":"Laboratory of Veterinary Anatomy, Faculty of Agriculture, Iwate University"}]},"item_16_version_type_27":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yamamoto, Yoshio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hatakeyama, Taku"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Taniguchi, Kazuyuki"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-11-14"}],"displaytype":"detail","filename":"nl-v454i2p129-133.pdf","filesize":[{"value":"265.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"nl-v454i2p129-133.pdf","url":"https://iwate-u.repo.nii.ac.jp/record/9095/files/nl-v454i2p129-133.pdf"},"version_id":"926917f1-3a35-49ff-8045-99272550375a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"TREK channel","subitem_subject_scheme":"Other"},{"subitem_subject":"TRP channel","subitem_subject_scheme":"Other"},{"subitem_subject":"Trigeminal ganglion","subitem_subject_scheme":"Other"},{"subitem_subject":"Thermosensation","subitem_subject_scheme":"Other"},{"subitem_subject":"Sensory nerve","subitem_subject_scheme":"Other"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Immunohistochemical colocalization of TREK-1, TREK-2 and TRAAK with TRP channels in the trigeminal ganglion cells","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Immunohistochemical colocalization of TREK-1, TREK-2 and TRAAK with TRP channels in the trigeminal ganglion cells"}]},"item_type_id":"16","owner":"3","path":["1510"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-09-14"},"publish_date":"2009-09-14","publish_status":"0","recid":"9095","relation_version_is_last":true,"title":["Immunohistochemical colocalization of TREK-1, TREK-2 and TRAAK with TRP channels in the trigeminal ganglion cells"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-05-16T11:15:46.369840+00:00"}