| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2012-02-17 |
| タイトル |
|
|
タイトル |
Measurement of the Rate of Myofibrillar Protein Degradation Using the Arteriovenous Difference in Plasma 3-Methylhistidine Concentration of Rats |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
arteriovenous difference |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
3-methylhistidine |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
myofibrillar protein degradation |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
leucine |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
SUGAWARA, Takayuki
ITO, Yoshiaki
NISHIZAWA, Naoyuki
SUZUKI, Hiromi
KOBAYASHI, Hisamine
NAGASAWA, Takashi
|
| 著者(機関) |
|
|
値 |
United Graduate School of Agricultural Sciences, Iwate University |
| 著者(機関) |
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|
値 |
Depatment of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University |
| 著者(機関) |
|
|
値 |
Depatment of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University |
| 著者(機関) |
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|
値 |
AminoScience Laboratories, Ajinomoto Co., Inc. |
| 著者(機関) |
|
|
値 |
AminoScience Laboratories, Ajinomoto Co., Inc. |
| 著者(機関) |
|
|
値 |
Depatment of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University |
| 登録日 |
|
|
日付 |
2012-02-17 |
| 書誌情報 |
Journal of Nutritional Science and Vitaminology
巻 55,
号 1,
p. 381-384,
発行日 2009-01-01
|
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0301-4800 |
| Abstract |
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|
内容記述タイプ |
Other |
|
内容記述 |
There are several methods for measuring the rate of myofibrillar protein degradation using 3-methylhistidine (3-MeHis) levels in urine, plasma and isolated muscle. However, these methods lack the accuracy of rate measurements. Therefore, it is necessary to develop a new method for determining the rate of myofibrillar protein degradation. We characterized an arteriovenous difference method using 3-MeHis plasma concentration. Rats were fasted overnight and subsequently administered leucine (135 mg/100 g BW) or fed a 20% casein diet. The rate of myofibrillar protein degradation was calculated by multiplying the femoral artery blood flow rate by the arteriovenous difference in 3-MeHis concentrations (vein−artery). The blood was collected from the femoral vein and abdominal aorta. The release of 3-MeHis from hindlimb muscle was significantly suppressed (p<0.05) in rats fed leucine or the 20% casein diet, indicating that myofibrillar protein degradation was suppressed. These results suggest that the evaluation of the rate of myofibrillar protein degradation using the arteriovenous difference method reflects nutritional conditions in a more physiological manner. |
| 出版者 |
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|
出版者 |
Center for Academic Publications Japan |
| 権利 |
|
|
権利情報 |
Copyright (c) 2009 by the Center for Academic Publications Japan |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.3177/jnsv.55.381 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
jnsv-v55n4p381-384.pdf (598.6 kB)
