{"created":"2023-05-15T12:05:05.904195+00:00","id":9713,"links":{},"metadata":{"_buckets":{"deposit":"0b67cdc8-4b7b-4025-bc86-539c7b4249b8"},"_deposit":{"created_by":3,"id":"9713","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"9713"},"status":"published"},"_oai":{"id":"oai:iwate-u.repo.nii.ac.jp:00009713","sets":["1515:1519"]},"author_link":["74171","74172","74173"],"item_16_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-01-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"106","bibliographicPageEnd":"15","bibliographicPageStart":"1","bibliographicVolumeNumber":"9","bibliographic_titles":[{"bibliographic_title":"BMC Neuroscience"}]}]},"item_16_date_6":{"attribute_name":"登録日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2009-02-27"}]},"item_16_description_12":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"Background: Multi-sensory integration is necessary for organisms to discriminate different\nenvironmental stimuli and thus determine behavior. Caenorhabditis elegans has 12 pairs of amphid\nsensory neurons, which are involved in generating behaviors such as thermotaxis toward\ncultivation temperature, and chemotaxis toward chemical stimuli. This arrangement of known\nsensory neurons and measurable behavioral output makes C. elegans suitable for addressing\nquestions of multi-sensory integration in the nervous system. Previous studies have suggested that\nC. elegans can process different chemoattractants simultaneously. However, little is known about\nhow these organisms can integrate information from stimuli of different modality, such as thermal\nand chemical stimuli.\n\nResults: We studied the behavior of a population of C. elegans during simultaneous presentation\nof thermal and chemical stimuli. First, we examined thermotaxis within the radial temperature\ngradient produced by a feedback-controlled thermoregulator. Separately, we examined chemotaxis\ntoward sodium chloride or isoamyl alcohol. Then, assays for simultaneous presentations of 15°C\n(colder temperature than 20°C room temperature) and chemoattractant were performed with\n15°C-cultivated wild-type worms. Unlike the sum of behavioral indices for each separate behavior,\nsimultaneous presentation resulted in a biased migration to cold regions in the first 10 min of the\nassay, and sodium chloride-regions in the last 40 min. However, when sodium chloride was\nreplaced with isoamyl alcohol in the simultaneous presentation, the behavioral index was very\nsimilar to the sum of separate single presentation indices. We then recorded tracks of single worms\nand analyzed their behavior. For behavior toward sodium chloride, frequencies of forward and\nbackward movements in simultaneous presentation were significantly different from those in single\npresentation. Also, migration toward 15°C in simultaneous presentation was faster than that in\n15°C-single presentation.\n\nConclusion: We conclude that worms preferred temperature to chemoattractant at first, but\npreferred the chemoattractant sodium chloride thereafter. This preference was not seen for\nisoamyl alcohol presentation. We attribute this phase-dependent preference to the result of\nintegration of thermosensory and chemosensory signals received by distinct sensory neurons.","subitem_description_type":"Other"}]},"item_16_publisher_14":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"BioMed Central Ltd."}]},"item_16_relation_26":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1186/1471-2202-9-106","subitem_relation_type_select":"DOI"}}]},"item_16_rights_18":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2008 Adachi et al; licensee BioMed Central Ltd."}]},"item_16_text_4":{"attribute_name":"著者(機関)","attribute_value_mlt":[{"subitem_text_value":"Laboratory of Bioscience, Faculty of Engineering, Iwate University"},{"subitem_text_value":"Department of Electrical and Electronic Engineering, Faculty of Engineering, Iwate University"},{"subitem_text_value":"Laboratory of Bioscience, Faculty of Engineering, Iwate University"}]},"item_16_version_type_27":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Adachi, Ryota"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Osada, Hiroshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shingai, Ryuzo"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-11-14"}],"displaytype":"detail","filename":"bmcn-ｖ9n106.pdf","filesize":[{"value":"3.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"bmcn-ｖ9n106.pdf","url":"https://iwate-u.repo.nii.ac.jp/record/9713/files/bmcn-ｖ9n106.pdf"},"version_id":"b23bbc1b-f925-45d8-8c41-91bcf395b8c8"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Phase-dependent preference of thermosensation and chemosensation during simultaneous presentation assay in Caenorhabditis elegans","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Phase-dependent preference of thermosensation and chemosensation during simultaneous presentation assay in Caenorhabditis elegans"}]},"item_type_id":"16","owner":"3","path":["1519"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-02-27"},"publish_date":"2009-02-27","publish_status":"0","recid":"9713","relation_version_is_last":true,"title":["Phase-dependent preference of thermosensation and chemosensation during simultaneous presentation assay in Caenorhabditis elegans"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-05-16T10:58:27.330445+00:00"}