| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2022-08-19 |
| タイトル |
|
|
タイトル |
Influence of dietary metformin on the growth performance and plasma concentrations of amino acids and advanced glycation end products in two types of chickens |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
amino acids |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
broiler |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Nε-(Carboxymethyl)lysine |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Glycation |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
layer |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
metformin |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
MAKINO, Ryosuke
UDA, Maaya
SHUTO, Syoko
KITA, Kazumi
TACHIBANA, Tetsuya
|
| 著者(機関) |
|
|
値 |
Department of Agrobiological Science, Faculty of Agriculture, Ehime University |
| 著者(機関) |
|
|
値 |
Department of Agrobiological Science, Faculty of Agriculture, Ehime University |
| 著者(機関) |
|
|
値 |
Department of Agrobiological Science, Faculty of Agriculture, Ehime University |
| 著者(機関) |
|
|
値 |
Department of Animal Science, Faculty of Agriculture, Iwate University |
| 著者(機関) |
|
|
値 |
Department of Agrobiological Science, Faculty of Agriculture, Ehime University |
| 登録日 |
|
|
日付 |
2022-08-19 |
| 書誌情報 |
Journal of Poultry Science
巻 58,
号 2,
p. 110-118,
発行日 2021
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13477439 |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
09167250 |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Glycation is a non-enzymatic reaction inducing the bonding of glucose to amino acids and proteins. Glycated amino acids are not useful for protein synthesis, suggesting that glycation reduces the utilization of amino acids. Metformin (MF) is well known as a therapeutic drug for type II diabetes that inhibits glycation. It is possible that treatment with MF raises the utilization of amino acids by the inhibition of glycation, thereby improving the growth performance of chickens. In the present study, therefore, we investigated the influence of dietary MF on the growth performance, and plasma concentrations of free amino acids and Nε-(Carboxymethyl)lysine (CML), which is an advanced glycation end product, in layer (Experiment 1) and broiler (Experiment 2) chickens. From 7 d of age, chicks were allowed free access to one of the experimental diets containing MF at 3 supplementation levels (0, 150, and 300 mg/kg diet) for 14 days. Body weight and feed intake were measured every week. At the end of the experiments, blood and breast muscle (M. pectoralis major) were collected for further analysis. Dietary MF did not affect weight gain, feed intake, or feed efficiency in both layer and broiler chickens. Dietary MF at the level of 150 mg/kg diet increased breast muscle weight in both layer and broiler chickens. Dietary MF increased plasma concentrations of branched chain amino acids and decreased concentrations of CML in layer chickens, although it did not affect plasma concentrations of glucose. The present study suggested that dietary MF might have the potency to increase breast muscle weight of layer chickens with an increment in plasma concentrations of branched-chain amino acids. |
| 抄録（URL） |
|
|
表示名 |
Influence of Dietary Metformin on the Growth Performance and Plasma Concentrations of Amino Acids and Advanced Glycation End Products in Two Types of Chickens |
|
URL |
https://www.jstage.jst.go.jp/article/jpsa/58/2/58_0200030/_article |
| 出版者 |
|
|
出版者 |
Japan Poultry Science Association |
| 権利 |
|
|
権利情報 |
Ⓒ 2021 Japan Poultry Science Association |
| 権利URI |
|
|
権利情報 |
https://creativecommons.org/licenses/by-nc-sa/4.0/ |
| NCID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA10796138 |
| NCID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11510037 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
info:doi/10.2141/jpsa.0200030 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
jps-v58n2p110-118 (142.3 kB)
