| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2009-10-09 |
| タイトル |
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|
タイトル |
CBF Change Evoked by Somatosensory Activation Measured by Laser-Doppler Flowmetry: Independent Evaluation of RBC Velocity and RBC Concentration |
| キーワード |
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|
主題Scheme |
Other |
|
主題 |
field potential |
| キーワード |
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主題Scheme |
Other |
|
主題 |
functional activation |
| キーワード |
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主題Scheme |
Other |
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主題 |
hide paw stimulation |
| キーワード |
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主題Scheme |
Other |
|
主題 |
laser-Doppler flowmetry |
| キーワード |
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主題Scheme |
Other |
|
主題 |
local cerebral blood flow |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
MATSUURA, Tetsuya
FUJITA, Hideaki
SEKI, Chie
KASHIKURA, Kenichi
YAMADA, Katsuya
KANNO, Iwao
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| 著者(機関) |
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|
値 |
Akita Laboratory, Japan Science and Technology Corporation, Akita Research Institute of Brain and Blood Vessels,
(Present address): Department of Welfare Engineering, Faculty of Engineering, Iwate University |
| 著者(機関) |
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|
値 |
Akita Laboratory, Japan Science and Technology Corporation, Akita Research Institute of Brain and Blood Vessels |
| 著者(機関) |
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値 |
Akita Laboratory, Japan Science and Technology Corporation, Akita Research Institute of Brain and Blood Vessels |
| 著者(機関) |
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値 |
Akita Laboratory, Japan Science and Technology Corporation, Akita Research Institute of Brain and Blood Vessels |
| 著者(機関) |
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|
値 |
Department of Physiology, School of Medicine, Akita University |
| 著者(機関) |
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値 |
Department of Radiology and Nuclear Medicine, Akita Research Institute of Brain and Blood Vessels |
| 登録日 |
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日付 |
2009-10-09 |
| 書誌情報 |
The Japanese Journal of Physiology
巻 49,
号 3,
p. 289-296,
発行日 1999-01-01
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| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0021-521X |
| Abstract |
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内容記述タイプ |
Other |
|
内容記述 |
The purpose of this study was to examine the timing and magnitude of neuronal activation. We measured the changes in local CBF(LCBF), red blood cell(RBC) velocity and RBC concentration by laser-Doppler flowmetry (LDF) as well as field potential recordings during activation of the somatosensory cortex of the rat in response to alactrical stimulation of the hind paw. Electrical stimuli, 0.1 ms pulses of 1-1.5 mA for 5 s, were applied at 0.2,0.5,5,10 and 50 Hz under α-chloralose anesthesia. LCBF showed the maximum increase at 5 Hz, and rose approximately 0.5 s after the onset of stimulation regardless of the frequency. The maximum freaquency of the filed potentials was also obtained at 5 Hz. During activation of the somatosensory cortex, the onset of rise in RBC concentration did not precede that of RBC velocity, and the peak RBC concentrasion was noted earlier than that both LCBF and RBC velocity, suggesting that both arteriolar diameter and active changes in the capillary contributed to the LCBF response. |
| 出版者 |
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出版者 |
日本生理学会 |
| DOI |
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関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
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関連識別子 |
10.2170/jjphysiol.49.289 |
| 著者版フラグ |
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出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
jjp-v49n3p289-296.pdf (581.5 kB)
