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Glycated Tryptophan PHP-THβC Incorporated into Various Chicken Embryonic Cells Constitutes Cellular Proteins
https://iwate-u.repo.nii.ac.jp/records/15508
https://iwate-u.repo.nii.ac.jp/records/155082ae03d0a-b83f-4195-958d-09d8f65f699e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
jps-v58n4p258-262 (310.6 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2022-01-11 | |||||
| タイトル | ||||||
| タイトル | Glycated Tryptophan PHP-THβC Incorporated into Various Chicken Embryonic Cells Constitutes Cellular Proteins | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | chicken embryo | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | glycation | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | PHP-THβC | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | protein synthesis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | tryptophan | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
MAKINO, Ryosuke
× MAKINO, Ryosuke× ABE, Kayoko× KITA, Kazumi |
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| 著者(機関) | ||||||
| 値 | Faculty of Agriculture, Iwate University, Faculty of Agriculture, Ehime University | |||||
| 著者(機関) | ||||||
| 値 | Faculty of Agriculture, Iwate University, Graduate School of Systems Life Sciences, Kyushu University | |||||
| 著者(機関) | ||||||
| 値 | Faculty of Agriculture, Iwate University | |||||
| 登録日 | ||||||
| 日付 | 2022-01-11 | |||||
| 書誌情報 |
The journal of poultry science 巻 58, 号 4, p. 258-262, 発行日 2021 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13490486 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13467395 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Glycation is a non-enzymatic reaction, and amino acids are glycated by glucose in vivo. Tryptophan is glycated with glucose to form two types of glycated compounds, tryptophan-Amadori product and (1R, 3S)-1-(D-gluco-1, 2, 3, 4, 5-pentahydroxypentyl)-1, 2, 3, 4-tetrahydro-β-carboline-3-carboxylic acid (PHP-THβC). Although PHP-THβC can be incorporated into various chicken embryonic cells, the mechanism of its incorporation into intracellular fluids has not been clarified. In this study, we examined whether PHP-THβC once incorporated into various chicken embryonic cells can combine with proteins. Embryonic cells from the breast muscle, liver, spleen, kidney, proventriculus, gizzard, and skin were prepared and 3H-PHP-THβC was added to the culture medium at final concentrations of 0, 200, 400, 600, and 800 µM to examine the incorporation of PHP-THβC. After 18 h of incubation, radioactivity was measured in the whole-cell and protein fractions of the chicken embryonic cells. As PHP-THβC concentration increased from 0 to 600 µM, its accumulation in the whole-cell fractions of all types of chicken embryonic cells linearly increased and reached the maximum level. The saturated PHP-THβC accumulation in the whole-cell fractions suggests that PHP-THβC could be incorporated into intracellular fluids across cellular membranes by some transporter proteins. As PHP-THβC concentration increased from 0 to 800 µM, its accumulation in the protein fractions of all types of chicken embryonic cells increased in a linear manner and reached a maximum level in the 800 µM PHPTHβC treatment group. This is the first study to indicate that a part of PHP-THβC incorporated into the whole-cell fraction was detected in the protein fraction of various chicken embryonic cells. | |||||
| 抄録（URL） | ||||||
| 表示名 | Glycated Tryptophan PHP-THβC Incorporated into Various Chicken Embryonic Cells Constitutes Cellular Proteins | |||||
| URL | https://www.jstage.jst.go.jp/article/jpsa/58/4/58_0200076/_article | |||||
| 権利 | ||||||
| 権利情報 | Ⓒ 2021 Japan Poultry Science Association | |||||
| 権利URI | ||||||
| 権利情報 | https://creativecommons.org/licenses/by-nc-sa/4.0/ | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA12018767 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA11564513 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | info:doi/10.2141/jpsa.0200076 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
