| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2022-09-15 |
| タイトル |
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|
タイトル |
The characteristic response of domestic cats to plant iridoids allows them to gain chemical defense against mosquitoes |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
UENOYAMA, Reiko
MIYAZAKI, Tamako
HURST, Jane L.
BEYNON, Robert J.
ADACHI, Masaatsu
MUROOKA, Takanobu
ONODA, Ibuki
MIYAZAWA, Yu
KATAYAMA, Rieko
YAMASHITA, Tetsuro
KANEKO, Shuji
NISHIKAWA, Toshio
MIYAZAKI, Masao
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| 著者(機関) |
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|
値 |
Department of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University |
| 著者(機関) |
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値 |
Department of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University |
| 著者(機関) |
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値 |
Mammalian Behaviour and Evolution Group, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus |
| 著者(機関) |
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値 |
Centre for Proteome Research, Institute of Systems, Molecular and Integrative Biology, University of Liverpool |
| 著者(機関) |
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値 |
Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University |
| 著者(機関) |
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値 |
Department of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University |
| 著者(機関) |
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値 |
Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University |
| 著者(機関) |
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|
値 |
Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University |
| 著者(機関) |
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値 |
Department of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University |
| 著者(機関) |
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値 |
Department of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University |
| 著者(機関) |
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値 |
Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University |
| 著者(機関) |
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|
値 |
Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University |
| 著者(機関) |
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|
値 |
Department of Biological Chemistry and Food Sciences, Faculty of Agriculture, Iwate University |
| 登録日 |
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|
日付 |
2022-09-15 |
| 書誌情報 |
Science Advances
巻 7,
号 4,
p. eabd9135,
発行日 2021
|
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
23752548 |
| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Domestic cats and other felids rub their faces and heads against catnip (Nepeta cataria) and silver vine (Actinidia polygama) and roll on the ground as a characteristic response. While this response is well known, its biological function and underlying mechanism remain undetermined. Here, we uncover the neurophysiological mechanism and functional outcome of this feline response. We found that the iridoid nepetalactol is the major component of silver vine that elicits this potent response in cats and other felids. Nepetalactol increased plasma β-endorphin levels in cats, while pharmacological inhibition of μ-opioid receptors suppressed the classic rubbing response. Rubbing behavior transfers nepetalactol onto the faces and heads of respondents where it repels the mosquito, Aedes albopictus. Thus, self-anointing behavior helps to protect cats against mosquito bites. The characteristic response of cats to nepetalactol via the μ-opioid system provides an important example of chemical pest defense using plant metabolites in nonhuman mammals. |
| 抄録（URL） |
|
|
表示名 |
The characteristic response of domestic cats to plant iridoids allows them to gain chemical defense against mosquitoes |
|
URL |
https://www.science.org/doi/10.1126/sciadv.abd9135 |
| 出版者 |
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|
出版者 |
American Association for the Advancement of Science |
| 権利 |
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|
権利情報 |
© 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. |
| 権利URI |
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|
権利情報 |
https://creativecommons.org/licenses/by-nc/4.0/ |
| DOI |
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|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
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関連識別子 |
info:doi/10.1126/sciadv.abd9135 |
| 著者版フラグ |
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出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
sa-v7n420peabd9135 (4.3 MB)
