| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2009-09-14 |
| タイトル |
|
|
タイトル |
Immunohistochemical colocalization of TREK-1, TREK-2 and TRAAK with TRP channels in the trigeminal ganglion cells |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
TREK channel |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
TRP channel |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Trigeminal ganglion |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Thermosensation |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Sensory nerve |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Yamamoto, Yoshio
Hatakeyama, Taku
Taniguchi, Kazuyuki
|
| 著者(機関) |
|
|
値 |
Laboratory of Veterinary Biochemistry and Cell Biology, Faculty of Agriculture, Iwate University |
| 著者(機関) |
|
|
値 |
Laboratory of Veterinary Anatomy, Faculty of Agriculture, Iwate University |
| 著者(機関) |
|
|
値 |
Laboratory of Veterinary Anatomy, Faculty of Agriculture, Iwate University |
| 登録日 |
|
|
日付 |
2009-09-14 |
| 書誌情報 |
Neuroscience Letters
巻 454,
号 2,
p. 129-133,
発行日 2009-01-01
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0304-3940 |
| Abstract |
|
|
内容記述タイプ |
Other |
|
内容記述 |
TREK belongs to a subfamily of tandem pore domain K+ channels, and consists of three subunits, TREK-1, TREK-2 and TRAAK. We examined the distribution of TREK-1, TREK-2 and TRAAK immunoreactive neurons in rat trigeminal sensory neurons. In the trigeminal ganglia, 31%, 43% and 60% of neurons were immunoreactive for TREK-1, TREK-2 and TRAAK, respectively. Mean sizes of TREK-1, TREK-2 and TRAAK immunoreactive trigeminal ganglion neurons were 447 ± 185, 445 ± 23 and 492 ± 12 mm2, respectively. Furthermore, TREK channels were colocalized with cationic TRP channels, TRPV1, TRPV2 and TRPM8. TREK-1 immunoreactive neurons were colocalized with TRPV1 (57%), TRPV2 (11%) and TRPM8 (33%). TREK-2-immunoreactive neurons were colocalized with TRPV1 (33%), TRPV2 (9%) and TRPM8 (19%). TRAAK immunoreactive neurons were colocalized with TRPV1 (47%), TRPV2 (10%) and TRPM8 (22%). The present results revealed that TREK-1, TREK-2 and TRAAK channels colocalized with thermosensitive TRP channels in some small trigeminal ganglion neurons. |
| 出版者 |
|
|
出版者 |
Elsevier |
| 権利 |
|
|
権利情報 |
© 2009 Elsevier Ireland |
| DOI |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1016/j.neulet.2009.02.069 |
| 著者版フラグ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
nl-v454i2p129-133.pdf (265.8 kB)
